Lipidic Cubic Phase (LCP) Screening Kit
The Lipidic Cubic Phase Crystallisation (LCP) kit from SWISSCI facilitates the automation and increased throughput of LCP crystallization set-ups. This novel system enables LCP screening to be performed accurately and with ease using manual or automated systems to complete the delivery of the solutions. Working with innovative scientists Professor Gebhard Schertler and Pat Edwards from the MRC Laboratory in Cambridge, Swissci AG developed a new system for setting up LCP screens.
The SWISSCI LCP kit ensures crystallography set-up is fast, cost-effective, and robotically adaptable. In addition, Ultra Violet light can be used with the glass / UVP polymers to visualize proteins without the light scattering associated with traditional polymeric solutions.
The LCP technique for crystallizing membrane proteins can be difficult and time-consuming to set up as it utilizes highly viscous lipid mesophases to reconstitute proteins. SWISSCI AG and MRC overcame these problems with the LCP kit. This product combines an easy to use sandwich system with dedicated coupling tapes and thin-film UVP cover plates. It conforms to ANSI/SLAS 1-2004-Standards and thus is perfect for modern automation applications where high throughput is required.
Ready to use, the plate fits laboratory robotics and uses a SWISSCI unique polymer to ensure UV stabilizations is not compromised by polarization.
Easy sealing with dry tabbed adhesive tape exposure and thin UVP cover film. Included in the kit is a plate leveling device to ensure the cover perfectly adheres to the bottom LCP plate.
No cross-contamination and ANSI/SLAS 1-2004-Standard.
The Sandwich plate can be easily removed from the base plate when required - in-situ X-ray data collection and structure determination are then enabled.
The product comprises a 700-micron thick UVP base plate with a 100 micron top pressure adhesive that has a yellow ready to remove the cover sheet and a separate 100-micron UVP cover film with protective dust cover. The kit is completed with a SWISSCI plate-leveling device.
Maximum volume of drop 1.6 microlitres.